The Thousand Faces of Invasive Group A Streptococcal Infections: Update on Epidemiology, Symptoms, and Therapy

Invasive infections caused by Streptococcus pyogfenes (iGAS), commonly known as Group A Streptococcus, represent a significant public health concern due to their potential for rapid progression and life-threatening complications.Epidemiologically, invasive GAS infections exhibit a diverse global distribution, affecting individuals of all ages with

read more

COVID-19 Prognosis in Children With Asthma

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a new coronavirus disease that is highly contagious and affects all Day Oil age groups of children.The incubation period of Coronavirus disease (COVID-19) ranges from 2 to 14 days.Diagnosis of COVID-19 is made by conducting nasal and pharyngeal swabs and analyzing sputum, stool, and bl

read more

Toll-like receptors of deuterostome invertebrates

Defensive systems against pathogens are responsible not only for survival or lifetime of an individual but also for the evolution of a species.Innate immunity is expected to be more important for invertebrates than mammals, given that adaptive immunity has not been acquired in the former.Toll-like receptors (TLRs) have been shown to play a crucial

read more

Analysis of ParB-centromere interactions by multiplex SPR imaging reveals specific patterns for binding ParB in six centromeres of Burkholderiales chromosomes and plasmids.

Bacterial centromeres-also called parS, are cis-acting DNA sequences which, together with the proteins ParA and ParB, are involved in the segregation of chromosomes and plasmids.The specific binding of ParB to parS nucleates the assembly of a large ParB/DNA complex from which ParA-the motor protein, segregates the sister replicons.Closely related f

read more

Analysis of Alternative Splicing and Alternative Polyadenylation in Populus alba var. pyramidalis by Single-Molecular Long-Read Sequencing

Poplars are worldwidely cultivated with ecologically and economically important value.Populus alba var.pyramidalis (= P.bolleana) is a main tree of tracer pellets the farmland shelter-belt system in the arid region of Northwest China due to its rapid growth, erect stems, and high biomass production.However, the full-length messenger RNA (mRNA) sequ

read more